Citric Acid Monohydrate

Product Description
Synonym: 2-Hydroxy-1,2,3-propanetricarboxylic acid monohydrate
Application: A useful buffer component for antigen and epitope unmasking
CAS Number: 5949-29-1
Purity: ≥98%
Molecular Weight: 210.14
Molecular Formula: C6H8O7•H2O

Citric Acid Monohydrate is an acidic compound from citrus fruits; as a starting point in the Krebs cycle, citrate is a key intermediate in metabolism. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates, and proteins to carbon dioxide and water. It has been used to prepare citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links, thus unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, and resulting in enhanced staining intensity of antibodies. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot. May be used to adjust pH and as a sequestering agent for the removal of trace metals.

Formula

Formula
Physical State : Solid
Solubility : Soluble in water (59.2 g/100 ml) at 20° C, ethanol, ether, and water (84.0 g/100 ml) at 100° C.
Storage : Desiccate at room temperature
Melting Point : 153° C(anhydrous)
Density : 1.54 g/cm3
Refractive Index : n20D 1.36 (lit.)

Citric Acid Anhydrous

Product Description
Synonym: Citrate; Aciletten
Application: Used in the preparation of citrate buffer for antigen and epitope unmasking in IHC
CAS Number: 77-92-9
Purity: >99%
Molecular Weight: 192.13
Molecular Formula: C6H8O7

Citric Acid is an acidic compound from citrus fruits; as a starting point in the Krebs cycle, citrate is a key intermediate in metabolism. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Often used to prepare citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links; thus, unmasking antigens and epitomes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot. May be used to adjust pH and as a sequestering agent for the removal of trace metals.

Formula

Formula
Physical State : Solid
Solubility : Soluble in alcohol, water (750 mg/ml at 20° C), and methanol. Insoluble in chloroform, and benzenz.
Storage : Desiccate at room temperature
Melting Point : 153-159° C (lit.)
Boiling Point : ~309.6° C at 760 mmHg (Predicted)
Density : 1.67 g/cm3 at 18° C (lit.)
Refractive Index : n20D 1.58 (Predicted)
IC50 : Fatso: IC50 = 300 µM (human); SRCAP: IC50 >40 mM (human)
Ki Data : Beta-lactamase: Ki= 490 µM (Bacillus licheniformis)
pK Values : pKa: 2.79, pK1: 3.13, pK2: 4.76, pK3: 6.4

Sodium Citrate

Product Description
Synonym: Citric acid monosodium salt
Application: A biological buffering agent resistant to changes in pH and sequestrant
CAS Number: 18996-35-5
Purity: ≥99%
Molecular Weight: 214.11
Molecular Formula: HOC(COONa)(CH2COOH)2

Sodium citrate monobasic is an acid salt with two open spots on the citrate anion, it is used as a relatively strong sequestrant. Sodium Citrate can perform as a biological buffering agent because it resists changes in pH. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot.

Formula

Formula
Appearance : Crystalline powder
Physical State : Solid
Solubility : Soluble in water
Storage : Store at room temperature

Potassium Citrate

Product Description
Application: A buffering agent and chelator
CAS Number: 866-83-1
Purity: ≥99%
Molecular Weight: 230.21
Molecular Formula: KH2C6H5O7

Potassium citrate is the potassium salt of citric acid. Used in the laboratory as a buffering agent and chelator. In renal function studies, it is used as an alkalizing agent where the citric acid is a metabolic substrate in renal cells. Studies have shown that potassium citrate may increase bone density, it is therefore used in research experiments related to the treatment of osteoporosis.

Formula

Formula
Appearance : Crystalline powder
Physical State : Solid
Solubility : Desiccate at room temperature
Storage : Store at room temperature

Sodium Citrate IP

Product Description
Application: A buffering agent and chelator
CAS Number: 866-83-1
Purity: ≥99%
Molecular Weight: 230.21
Molecular Formula: KH2C6H5O7

Potassium citrate is the potassium salt of citric acid. Used in the laboratory as a buffering agent and chelator. In renal function studies, it is used as an alkalizing agent where the citric acid is a metabolic substrate in renal cells. Studies have shown that potassium citrate may increase bone density, it is therefore used in research experiments related to the treatment of osteoporosis.

Formula

Formula
Appearance : Crystalline powder
Physical State : Solid
Solubility : Desiccate at room temperature
Storage : Store at room temperature

Di Sodium Hydrogen Citrate BP

Product Description
Synonym: Citric acid monosodium salt
Application: A biological buffering agent resistant to changes in pH and sequestrant
CAS Number: 18996-35-5
Purity: ≥99%
Molecular Weight: 214.11
Molecular Formula: HOC(COONa)(CH2COOH)2

Sodium citrate monobasic is an acid salt with two open spots on the citrate anion, it is used as a relatively strong sequestrant. Sodium Citrate can perform as a biological buffering agent because it resists changes in pH. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot.

Formula

Formula
Appearance : Crystalline powder
Physical State : Solid
Solubility : Soluble in water
Storage : Store at room temperature